About Bisacodyl Diphenyl methane derivative ,Stimulant (irritant)Laxative Mechanism of Action of Bisacodyl Bisacodyl is a stimulant (irritant) laxative. It acts directly on the colonic mucosa-where it stimulates sensory nerve endings in the walls of the intestine and the rectum to produce parasympathetic reflexes resulting in increased peristaltic contractions of the colon and cause defecation. Indications for Bisacodyl 1.Bowel evacuation in prior to radiological examinations 2.Constipation 3.Laxative in postoperative, ante partum, or postpartum care Contra-indications of Bisacodyl 1.Hypersensitivity to Bisacodyl 2.Intestinal obstruction 3.Obstruction of the intestines due to loss of intestinal movement 4.Severe dehydration 5.Sudden abdominal conditions requiring surgery (appendicitis) 6.Sudden attacks of inflammatory bowel disease (ulcerative colitis or Crohn`s disease) 7.Anal fissure 8.Ulcerative proctitis